Keratin 10 Antikörper

Produktnummer ABIN6297643

Dieser Maus Monoklonal Antikörper erkennt spezifisch Keratin 10 in IHC, IF und FACS. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Keratin 10 Antikörper (ABIN6297643)

Target: Keratin 10 (KRT10)

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Keratin 10 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-Keratin 10 Antikörper

Verwendungszweck: Mouse anti-Human/Mouse Cytokeratin 10 Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: Skin extract of a human Psoriasis patient were used as the immunogen for this Cytokeratin 10 antibody.

Immunogen: Skin extract of a human Psoriasis patient were used as the immunogen for this Cytokeratin 10 antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.1-0.2 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Keratin 10

Target: Keratin 10 (KRT10)

Andere Bezeichnung: Keratin, type I cytoskeletal 10

Hintergrund:

Target Description: CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

Gene Symbol: KRT10///KPP

Gen-ID: 3858

UniProt: P13645